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Leksell Gamma Knife^® Esprit

Leksell Gamma Knife® Esprit – The Evolution of Gamma Knife for Modern Neuroradiosurgery

Leksell Gamma Knife® Esprit is not just a new generation of Gamma Knife, but a technological evolution of the entire Elekta stereotactic radiosurgery platform.
Compared to previous generations, Esprit expands clinical capabilities by combining submillimeter Gamma Knife precision, frameless and frame-based workflows, integrated advanced planning, improved clinical efficiency for single and multi-fraction treatments, and greater adaptability for complex clinical scenarios.

Frameless and Frame-Based Treatment in a Single System

One of the key advantages of Gamma Knife® Esprit is support for both traditional frame-based and modern frameless workflows. This opens new opportunities for clinics:

More flexible treatment protocol selection;
Broader application of single-session and fractionated SRS;
Better adaptation to anatomy, clinical objectives, and patient condition;
Higher patient comfort without compromising accuracy.

Submillimeter Precision of Gamma Knife – Esprit

Maintains the key advantage of the Gamma Knife platform — exceptional dose delivery accuracy for intracranial targets. The system uses 192 simultaneous high-energy gamma beams, ensuring:

High conformity of dose distribution;
Minimization of dose to healthy tissues;
Ability to treat small, multiple, and anatomically complex targets;
High confidence when working near critical structures.

Expansion of Clinical Scenarios

Previous Gamma Knife generations were primarily focused on single-session frame-based radiosurgery. Esprit expands this concept and better meets modern neuroradiosurgery requirements.
The platform is especially valuable for centers working with:

Multiple brain metastases;
Large lesions near critical structures;
Benign skull base tumors;
Functional indications;
Cases requiring greater flexibility in treatment strategy.

Enhanced Patient Comfort

Compared to previous Gamma Knife generations, Esprit offers a more modern patient-centered approach.
This is especially important in cases where mask-based / frameless workflow is appropriate, allowing:

Reduced psychological burden;
Expanded possibilities for treatment personalization;
Improved overall treatment experience.

Technical Specifications

The main technological features of Leksell Gamma Knife® Esprit combine the proven physical architecture of Gamma Knife with updated clinical logic.
Key technical parameters:

192 simultaneous gamma beams for high-precision dose delivery
Submillimeter accuracy for intracranial targets
Support for frame-based and frameless treatment
Integrated platform for treatment planning and delivery
Support for single-session and multi-session / staged treatment scenarios
Focus on high dose conformity and protection of healthy tissues

Clinical Indications

A system for a wide range of intracranial pathologies. Leksell Gamma Knife® Esprit is used for high-precision treatment of intracranial conditions, including:

Brain metastases
Meningiomas
Vestibular schwannomas
Arteriovenous malformations (AVM)
Pituitary adenomas
Trigeminal neuralgia
Other benign, malignant, and functional intracranial pathologies

Linear Accelerator Elekta Harmony

Modern High-Precision Radiation Therapy System

Elekta Harmony is an innovative high-precision radiotherapy system that combines treatment speed, clinical accuracy, and patient comfort. The system is designed for the effective treatment of a wide spectrum of oncological diseases using advanced radiotherapy and imaging technologies.

Elekta Harmony provides an optimal balance between performance, precision, and ease of use, allowing complex radiotherapeutic procedures to be performed quickly, safely, and with maximum efficiency.

High Treatment Precision

High-precision dose shaping with a resolution of up to 1 mm
Accurate dose delivery to the tumor while sparing healthy tissues
Advanced technologies for patient and target position control
High compliance between the treatment plan and actual irradiation

Harmony provides precision irradiation of even complex targets, increasing treatment efficacy and reducing the risk of complications.

Speed and Efficiency

Reduction of patient preparation time by up to 50%
Most standard procedures take less than 10 minutes
High dose rate delivery
Optimization of clinical workflows

Patient Comfort

Fast treatment sessions
Reduced time on the treatment couch
Modern design and ergonomics
High positioning accuracy

Treatment Technologies

Harmony supports modern radiotherapy techniques that meet international standards of oncological care:

IMRT Allows precise modulation of radiation intensity and adaptation to the shape of the tumor.

VMAT Provides fast and uniform irradiation during gantry rotation with high precision.

IGRT Uses 2D and 3D visualization for accurate positioning before each procedure.

Dynamic Conformal Arc Therapy and Gated Therapy (respiratory motion management)

Clinical Indications

The Harmony linear accelerator is used to treat most oncological diseases:

head and neck tumors
brain tumors
breast cancer
lung cancer
prostate cancer
abdominal tumors
gynecological oncological diseases
palliative radiation therapy

The system allows treatment of both localized and advanced tumor processes

Harmony provides an integrated treatment and quality control system that meets modern international radiotherapy standards. The Harmony linear accelerator represents a modern standard in radiotherapy, combining advanced technology and clinical efficiency for the safe and accurate treatment of oncological diseases.

Linear Accelerator Elekta Harmony Pro

High-Performance Linear Accelerator for Radiotherapy

Elekta Harmony Pro is a modern linear accelerator designed to provide effective treatment and optimize clinical workflows within radiotherapy departments. The system combines high performance, ease of use in the treatment room, and automation tools for key stages of treatment preparation and control.

Optimization of the Treatment Process

Harmony Pro supports a reduction in the duration of treatment preparation and delivery, which is a critical factor for increasing departmental throughput and maintaining clinical schedule stability.
FastTrack technology provides up to a 50% reduction in setup time* and facilitates more effective staff-patient interaction during session preparation.
Ability to treat the most common clinical indications in under 10-minute intervals, utilizing a single arc, single isocenter, and a single treatment plan.

Integrated Quality Assurance (QA)

The system features rapid and integrated quality assurance, enabling the automation and standardization of control procedures while simplifying QA processes during equipment operation.

Comprehensive Lifecycle Solution

Harmony Pro is more than just a linear accelerator; it is a suite of solutions covering the primary stages of system utilization—from commissioning to scheduled technical support and equipment performance optimization throughout its entire lifecycle.
Efficient system startup and organization with the Harmony START program.
Optimized support for reliable and predictable technical maintenance throughout the entire service life.
Beam matching capability between accelerators to enhance the operational efficiency of the radiotherapy department.

Intelligent dashboards for data access, monitoring, and analysis, regardless of the user's location.

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About Company

BIOSENS LLC is a Ukrainian company in the field of medical technologies, specializing in solutions for radiation therapy and radiosurgery. Since 2011, the company has been implementing and supporting high-tech equipment for the treatment of oncological diseases.
BIOSENS is an official partner of leading global manufacturers, including Elekta, C-RAD, MacroMedics, Sun Nuclear, and Beekley, and acts as an integrator of comprehensive solutions, combining engineering, clinical, and service expertise at all stages of project implementation — from consulting to long-term technical support.
The company’s solutions have been implemented in more than 30 medical institutions. Over 40 linear accelerators, brachytherapy systems, and patient positioning control technologies are under service support. The company ensures up to 95% equipment availability and prompt service support with a response time of up to 24 hours.

Areas of Cooperation